From Tissue Engineering to Regenerative Surgery

I Martin,M Jakob,D.J Schaefer

doi:10.1016/j.ebiom.2018.01.029

Abstract

From Tissue Engineering to Regenerative Surgery

Highlights

The study elegantly describes the surgical tools introduced to manipulate the site of implantation and openly reports the need to adapt the complex surgical procedure to the specific patient conditions, to the extent that three different
In line with similar developments for nasal cartilage restoration (Fulco et al, 2014), the authors confirm the importance to operate a transition from the classical view of tissue engineering, centered on the manufacturing of a suitable graft, towards a more comprehensive paradigm, which can be referred to as “regenerative surgery”
The phrase captures that surgical manipulation of an engineered graft, preparation and conditioning of the environment at the recipient site and reaction of the surrounding soft tissue over time, are at least as critical as the manufactured implant and its designed functionalities

Summary

Introduction

The study elegantly describes the surgical tools introduced to manipulate the site of implantation (e.g., tissue expanders, skin grafts) and openly reports the need to adapt the complex surgical procedure to the specific patient conditions, to the extent that three different. Methods were applied for the five patients treated. In line with similar developments for nasal cartilage restoration (Fulco et al, 2014), the authors confirm the importance to operate a transition from the classical view of tissue engineering, centered on the manufacturing of a suitable graft, towards a more comprehensive paradigm, which can be referred to as “regenerative surgery”.

Results

Conclusion