Abstract

The development of the Digital Brain Library (DBL), envisaged as a permanent archive that describes the spectrum of normal brain maturation, aging and neurological disease, is described. The DBL is composed of individual brain atlases, constructed by the combined techniques of magnetic resonance imaging (MRI) and computer-controlled microscopy to show the brain at multiple levels of resolution, in 2-D and 3-D. The archive contains quantitative parameters that are linked to the results of neuropsychological and attitudinal tests as well as biographical records obtained from the individuals who donated the brain to the collection. Data exploration is supported by statistical tools and web technologies that maximize the utilization of the collection at different levels of expertise.

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