Abstract

It is hard to overestimate the impact the discovery and commercial development of penicillin have had on humanity. We do not worry about dying from bacterial infection as we did before the age of antibiotics. Penicillin was discovered by bacteriologist Alexander Fleming in 1928. Working in his lab at St. Mary’s Hospital in London, Fleming observed that the fungus Penicillin notatum prevented the growth of Staphylococcus bacterial colonies. But it wouldn’t be until the 1940s that reliable methods for fermenting the drug were scaled up so it could be administered to patients. The effort was centered in the US, as the UK was too close to the war in Europe for such an endeavor, and involved the US government and drug companies such as Abbott Laboratories, Merck & Co., E.R. Squibb, and Pfizer. In fact, Pfizer’s development of deep-tank fermentation to make penicillin was named an American Chemical Society National

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