Abstract
The aim: Evaluate the diagnostic capabilities of the ChatGPT in the field of medical diagnosis. Materials and methods: We utilized 50 clinical cases, employing Large Language Model ChatGPT-3.5. The experiment had three phases, each with a new chat setup. In the initial phase, ChatGPT received detailed clinical case descriptions, guided by a "Persona Pattern" prompt. In the second phase, cases with diagnostic errors were addressed by providing potential diagnoses for ChatGPT to choose from. The final phase assessed artificial intelligence's ability to mimic a medical practitioner's diagnostic process, with prompts limiting initial information to symptoms and history. Results: In the initial phase, ChatGPT showed a 66.00% diagnostic accuracy, surpassing physicians by nearly 50%. Notably, in 11 cases requiring image inter¬pretation, ChatGPT struggled initially but achieved a correct diagnosis for four without added interpretations. In the second phase, ChatGPT demonstrated a remarkable 70.59% diagnostic accuracy, while physicians averaged 41.47%. Furthermore, the overall accuracy of Large Language Model in first and second phases together was 90.00%. In the third phase emulating real doctor decision-making, ChatGPT achieved a 46.00% success rate. Conclusions: Our research underscores ChatGPT's strong potential in clinical medicine as a diagnostic tool, especially in structured scenarios. It emphasizes the need for supplementary data and the complexity of medical diagnosis. This contributes valuable insights to AI-driven clinical diagnostics, with a nod to the importance of prompt engineering techniques in ChatGPT's interaction with doctors.
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