Abstract
Systemic lupus erythematosus (SLE), a complicated autoimmune disease with multiple organ involvement, is characterized by excessive autoantibody production and immune complex deposition. According to the European League Against Rheumatism and the American College of Rheumatology classifications of SLE, clinical manifestations and immunological indicators are two major criteria for lupus classification. A 7-year-old patient presented by Brown et al. exhibited thrombocytopenia, hypocomplementemia, and elevated autoantibodies, which are critical serological features of lupus.
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