From Lipids to Micelles- A Tentative Analysis of Drug Delivery

Abstract

Polymer micelles (PM) are core-shell nanostructures formed by the self-assembly of amphiphilic block copolymers. Due to its hollow form and biocompatibility, it is an excellent drug carrier and has a wide range of uses in the pharmaceutical field. This review summarizes the latest developments in PM development and its applications. First, I explained the basic structure and several types of micelles. This process introduces experiments and parameters to control the shape of the vesicles used for drug delivery. Next, we talked about various common synthetic methods such as the solvent conversion method and the solvent-free method. In addition, we introduce polymer micelles into conventional pharmacies and the difficulties of modern medicine. Finally, it summarizes the morphology, synthesis method and application of PM in the medical field, and provides insights into the future development of vesicle degradation and the biocompatibility of PM preparation and the resulting morphology. In addition to the above, this article also introduces different methods of PM targeting, imaging, and triggered release in pharmaceutical applications.