Abstract
Meeting abstracts The major histocompatibility complex and the leukocyte receptor complex are the two most polymorphic regions of the immune genome. Individuals with increasingly diverse repertoires of MHC class-I molecules have a greater potential for their natural killer (NK) cells to be more
Highlights
From 30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015) National Harbor, MD, USA. 4-8 November 2015
natural killer (NK) cell activity is under complex regulation of NK cell education that is fine-tuned by tumor microenvironment
We investigated the mechanisms of local tumor antigenspecific T cell-NK cell collaboration, which appeared indispensable for the elimination of tumor cells, including antigen-deficient tumor escape variants that arise before metastasis
Summary
From 30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015) National Harbor, MD, USA. 4-8 November 2015. From immunogenetic polymorphism to functional antitumor lymphocyte mitochondrial dynamics Roman Uzhachenko1, Menaka Thounaojam1, Anil Shanker1,2* From 30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015) National Harbor, MD, USA.
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