Abstract
The Friedel-Crafts acylation reaction is one of the most important in aromatic chemistry used in particular to prepare aryl ketones. The major drawback of the Friedel-Crafts reaction lies in the need to use the Lewis acid in stoichiometrical quantities relative to the acetone formed, which in industrial terms poses large effluent problems. The use of stoichiometrical quantities of Lewis acid results in the formation of a complex at the end of the reaction between the aryl ketone formed and the Lewis acid. To resolve the effluent problem, much work has been performed investigating the conditions or catalysts that enable the Friedel-Crafts acylation to be performed with catalytic quantities of Lewis acid.
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