Abstract

BACKGROUND CONTEXT Application of nerve root block mainly for the diagnosis but less application in intraoperative treatment. PURPOSE To observe the effect of application of gelatin sponge impregnated a mixture of three drugs (GSIAM) to intraoperative nerve root block to promote early postoperative recovery of lumbar disc herniation (LDH). STUDY DESIGN/SETTING A total of 265 patients with single-level LDH were retrospectively analyzed from January 2013 to October 2017. Patients were divided into intervention group and control group according to whether intraoperative GSIAM. PATIENT SAMPLE A total of 265 patients with single-level LDH were retrospectively analyzed from January 2013 to October 2017. Patients were divided into intervention group and control group according to whether intraoperative GSIAM. OUTCOME MEASURES All patients underwent unilateral MIS-TLIF surgery. Clinical data such as bedbound period, postoperative hospital stays, VAS score of low back pain and leg pain, JOA score, postoperative satisfaction questionnaire results, and therapeutic effect were collected. METHODS A total of 265 patients with single-level LDH were retrospectively analyzed from January 2013 to October 2017. Patients were divided into intervention group and control group according to whether intraoperative application of GSIAM. All patients underwent unilateral MIS-TLIF surgery. Clinical data such as bedbound period, postoperative hospital stays, VAS score of low back pain and leg pain, JOA score, postoperative satisfaction questionnaire results, and therapeutic effect were collected. RESULTS A total of 136 cases were included in the intervention group. A total of 129 cases were included in the control group. The intervention group had significantly shorter bedbound period and postoperative hospital stays than the control group (P CONCLUSIONS Application of GSIAM to intraoperative nerve root block can significantly promote the early postoperative recovery of LDH, and has great short-term clinical efficacy.

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