Abstract
BACKGROUND CONTEXT The Patient-Reported Outcomes Measurement Information System (PROMIS) utilizes standardized T-scoring in assessing patient quality of life. The utility of PROMIS, and its relation to established Health Related Quality of Life metrics (HRQoLs), is poorly understood in populations of varying combinations of spinal diagnoses. PURPOSE We compared PROMIS to established HRQoLs (ODI and EQ5D) in the ability to capture differences between degenerative disc disease (DDD), herniated disc (HNP), degenerative spondylolisthesis (DSPL), and spinal canal stenosis (LS) diagnoses. STUDY DESIGN/SETTING Retrospective review. PATIENT SAMPLE A total of 302 patients. OUTCOME MEASURES EQ5D, EQ5D visual analog scale (EQ5D VAS), Oswestry Disability Index (ODI), PROMIS Physical Function, PROMIS Pain Intensity, PROMIS Pain Interference. METHODS A retrospective chart review was conducted (Dec 2016–Jul 2017). Inclusion: patients with DDD, HNP, DSPL, or LS diagnoses and completed HRQoL data (EQ5D, EQ5D VAS, ODI, PROMIS). Correlation analysis determined relation between all HRQoL metrics. Unpaired t-test analysis compared patients diagnosed with and without DDD, HNP, DSPL or LS. Unpaired t-tests compared patients with one of the mentioned diagnoses versus all combinations of two of these diagnoses. RESULTS A total of 302 patients with a diagnosis of DDD (n=137), HNP (n=105), DSPL (n=98), or LS (n=224) were included (mean age: 62.7, 51.3%F). In our overall population, PROMIS categories significantly correlated with EQ5D and ODI categories. PROMIS physical functioning correlated with EQ5D VAS (R=0.331, P CONCLUSIONS PROMIS scores correlate to previously established HRQoL metrics (EQ5D and ODI) in patients diagnosed with herniated disc, degenerative disc disease, spondylolisthesis and spinal canal stenosis. PROMIS scores were the only HRQoL metrics to differentiate herniated disc and spinal canal stenosis diagnoses. Further, PROMIS scores, and not EQ5D or ODI, were able to capture the difference between patients presenting with herniated disc and those presenting with both herniated disc and spinal canal stenosis.
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