Abstract
Skin can be damaged by the environment easily. Skin cream is an effective and rapid way to moisten the skin by changing the skin surface properties. Rat skin and pig skin are common animal models for studies and were used as skin samples in this study. The nano- and macroscale friction and durability of damaged skin were measured and compared with those of virgin (intact/undamaged) skin. The effect of skin cream on friction and durability of damaged and virgin skin samples is discussed. The effects of velocity, normal load, relative humidity and number of cycles were studied. The nanoscale studies were performed by using atomic force microscope (AFM), and macroscale studies were performed by using a pin-on-disk (POD) reciprocating tribometer. It was found that damaged skin has different mechanical properties, surface roughness, contact angle, friction and durability compared to that of virgin skin. But similar changes occur after skin cream treatment. Rat and pig skin show similar trends in friction and durability.
Highlights
Under the same displacement control, the load required for a given displacement for pig skin is larger than that for the rat skin, which means the pig skin is harder than rat skin
Both the nanohardness and elastic modulus of pig skin samples are higher than those of rat skin samples, and those of the damaged skin are higher than virgin skin for both rat and pig skin
The effect of velocity, normal load, and relative humidity on the coefficient of friction for virgin skin, cream-treated virgin skin, damaged skin and cream-treated damaged skin were studied on the nano- and macroscale
Summary
Normal load, relative humidity and number of cycles on nanoscale friction Figure 6a shows the coefficient of friction as a function of velocity for various skin samples. As discussed earlier, the levels of the fragile corneocytes generally increase, so the stratum corneum of damaged skin is torn rapidly at high loads in macroscale experiments forming a lubricant layer between the tip and the skin surface, which is more sheared, and may compensate the loss of the lipid layer.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
