Abstract
Background The incidence of gout in China is increasing in adults as well as children. The clinical manifestations of juvenile gout are not well described due to the limited number of cases in the past. Delineating the features of adult and juvenile gout may help pediatric providers recognize gout more effectively. Objectives We aim to describe and compare the clinical characteristic of adults and children with gout. Methods A total of 51 juvenile gout patients (age ≤ 18 years) and 337 adult gout patients in our hospital from Jan 2016 to Dec 2018 were enrolled in the study. Clinical parameters and laboratory data of the 2 groups were analyzed. Results The average age of onset in children with gout was 15.0±1.9 years and the youngest patient was 8 years old. Compared to the adult group, juvenile gout patients displayed lower BMI (23.0±3.8 vs. 25.6±3.5 kg/m2, P Conclusion Juvenile gout is associated with higher serum uric acid levels and greater involvement of finger joints. Correlations with BMI and systemic inflammation were less prominent compared to gout in adults. These findings will help clinicians better recognize gout in children.
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