FRI0392 The specific role of glutaredoxin2 isoform B (GLRX2B) in rankl-induced osteoclastogenesis through activation of the P38-MAPK signaling pathway

Abstract

BackgroundRecently, reactive oxygen species (ROS) and antioxidant enzymes were shown to be closely associated with RANKL-mediated osteoclast differentiation. Although glutaredoxin2 (Glrx2) plays a role in cellular redox homeostasis, its role...