Abstract
Background Progressive systemic sclerosis (SSc) is a connective tissue disease where fibrosis of skin and internal organ is a hallmark of disease activity. One of the most affected system in the patients is the alimentary tract. Objectives The aim of the study was to determine self-related contraction and motor activity between stomach and gallbladder. Methods Study was performed in a group of twelve patients with SSc. Twelve sex- and age-matched healthy volunteers served as the controls. Gallbladder volume and emptying was assessed after ingestion of fat-rich 300 ml semi-liquid fluid. Changing cross section antrum diameter was measured in the same time. Results Delayed gastric emptying in patients with SSc was shown. Impaired gastric activity was especially seen in early and late phases of gastric emptying (p. Conclusion Gastric motility disturbances observed in patients with SSc are mainly due to its involvement in the course of disease. We postulate that slightly impaired gallbladder function did not augment gastric contraction impairment.
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