FRI0069 Neutrophils play a key role in the regulation of the chronic inflammation associated with rheumatoid arthritis through epigenetic mechanisms modulated by anti-ccps antibodies and reversed by biologic therapies

Abstract

BackgroundMicroRNAs (miRNA) are as a new class of modulators of gene expression, regulating inflammation, degradation of extracellular matrix and invasive behavior of the resident cells in rheumatoid arthritis (RA).Objectives1) To...