FRI0032 Increased level of IL-34 in serum and synovial fluid is associated with rheumatoid factor and anti-cyclic citrullinated peptide antibodies titer in patients with rheumatoid arthritis

Abstract

BackgroundInterleukin-34 (IL-34) is a recently discovered cytokine that binds macrophage colony-stimulating factor (M-CSF). Rheumatoid arthritis (RA) is a representative inflammatory arthritis characterized by increased osteoclastogenesis, which contributes to joint destruction...