Abstract
This study characterized how porcine teschovirus (PTV) contributed to causing nonsuppurative encephalitis in the endemic field situation which was mostly subacute to chronic. Tissues from 57 encephalitic pigs, in the years 2005–2008, were randomly selected for detection of PTV antigens by immunohistochemistry. In only 3/57 (5.3%) pigs PTV signal was detected in brain cells of noninflammatory sites. On the other hand, PTV signals were present at significant rates in visceral and lymphoid organs. Spleen (33.3%), lung (24.6%) and kidney (14%) were among the higher, while those of lymphoid organs were 17.5%–26.3%, and intestines were 21.1%–24.6%. Nursery pigs not only comprised a bulk of the samples (n = 26), but also had a higher signal detection rate of 53.8% (by head) and average numbers of 2.65 positive organs per animal. Cellular tropism and antigen localization of PTVs are closely related to viremia, fecal and urinal sheddings, reinfection and recirculation of PTV within the herd.
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