Frequency of Triple Vessel Coronary Artery Disease in Diabetic and Non Diabetic Patients Presenting with NSTEMI

Abstract

Multi-vessel coronary artery disease (MVD) has profound challenges to the revascularization system. Several investigations showed diverse forms of CAD associated with complete or incomplete revascularization in MVD in PCI. Diabetic patient had more multi-vessel CAD as compared to non-diabetics. Objectives: To determine the frequency of triple vessel coronary artery disease and afterwards compare the triple vessel coronary artery disease in diabetic v/s non-diabetics in patients presenting with NSTEMI. Methods: This Descriptive Cross-Sectional Study was conducted at Emergency Department of the National Institute of Cardiovascular Diseases (NICVD), Karachi for Six months from March 4, 2019, to September 3, 2019. Samples size n=250 was calculated through non-probability consecutive sampling technique. All the patients of either gender presenting NSTEMI and undergone coronary angiography, aged >40 and < 75 years and agreed to participate after their volunteer affirmation were included in this study. Results: Out of 250 patients, 75.6% were male while 24.4% were female with a mean age of 56.60. Triple Vessel Disease was documented in 107(42.8%) patients. As for the study main objective variable diabetes, the comparative analysis of triple vessel disease between diabetic versus non-diabetic resulted in significant difference was noted i.e., p-value =0.030. Conclusions: Diabetic Mellitus has a significant factor for 3VD among the patients of NSTEMI patients. As a risk factor and comorbid, DM screening is a necessary factor in all NSTEMI patients who diagnosed with 3VD.