Abstract
This study aims to detect USP6 translocation in aneurysmal cysts located in the jaw and to give an overview of demographic data. The present retrospective cohort study includes 10 patients who underwent surgery due to an aneurysmal cyst of the jaw in our hospital between 2002 and 2021. Unstained formalin-fixed and paraffin-embedded tissue sections cut at 4μm thickness were subjected to USP6 FISH testing. All patients underwent surgical treatment. In four of ten patients (40%) USP-6-translocations have been found. Based on the study, it is hypothesized that the aneurysmal bone cyst of the jaw bone may be subject to a different pathomechanism than that of the long bones. Therefore, it seems conceivable that the primary cause of aneurysmal bone cysts in the jaw might differ.
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Schedule a callMore From: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
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