Frequency of methicillin-resistant staphylococcus aureus carriage state in patients of a cancer hospital.

Abstract

e15086 Background: Methicillin-resistant staphylococcus aureus (MRSA) is one of the most frequent multi-drug resistant pathogens of nosocomial infections. Examination of all coming patients for MRSA carriage state is not obligatory in Russia, though it is the necessary part of MRSA prevention programs. The purpose of the study was to assess the level of methicillin-resistant staphylococcus aureus carriage state in patients of a cancer hospital. Methods: Nasal and throat washings, secretions from surgical wound drainage were used as the material for the study. Presence and content of staphylococcus aureus DNA fragments and mecA gene were detected with Real-time PCR method. 141 samples were examined. Results: 56% of patients coming to the hospital were initially colonized with MRSspp., including MRSA in 12%. During the next examination of nasal washings, MRSA colonization was detected in 30% of patients while in hospital. During the examination of secretions from drainage, MRSspp. were detected in 44,2% of ...