Frequency of iron deficiency anemia (IDA) among patients with Helicobacter pylori infection.

Adeel Rahat,Lubna Kamani

doi:10.12669/pjms.37.3.3944

Abstract

Background and Objective:Helicobacter Pylori (H. pylori) is a widespread infection across the globe having a high prevalence among the developing countries. Iron Deficiency is anticipated to be the most prevalent micronutrient deficiency globally, the most frequent cause of anemia. Our objective was to determine frequency of Iron Deficiency Anemia (IDA) among patients with H. Pylori gastritis.Methods:It was a cross-sectional prospective study. Patients fulfilling inclusion criteria were enrolled at Liaquat National Hospital, Karachi, Pakistan. Blood samples were taken for serum iron, transferrin saturation, ferritin, and total iron-binding capacity and H.pylori assessed by urea breath test, stool for antigen, Rapid urease test or histopathology.Results:112 patients with H. Pylori infection with anemia were included. 53 (47.3%) were males & 59 (52.7%) were females with mean age of 38.4464 ± 9.00634 years. Iron deficiency anemia was seen in 42 patients (37.5%).Conclusion:IDA was noted in 37.5% of cases. H. Pylori infection is a frequent cause of iron-deficiency anemia of previously unidentified origin among adults.

Highlights

This study evaluated the frequency of Iron Deficiency Anemia (IDA) among anemic patients with H
Blood samples were collected for calculating serum iron and ferritin concentrations, transferrin saturation, and total iron-binding capacity (TIBC)
Percentages and frequencies were recorded for categorical variables like gender, education level, socioeconomic status, hemoglobin levels, and other parameters like serum Iron, Ferritin, transferrin saturation, and TIBC levels, iron deficiency anemia

Summary

Introduction

H. Pylori is a chronic microbial infection, which is highly prevalent around the globe, especially in developing countries. Though high variation has been associated with age, geography, and socioeconomic status, its overall prevalence is high in developing countries due to many reasons.[1]. Helicobacter Pylori (H. pylori) is a widespread infection across the globe having a high prevalence among the developing countries. Iron Deficiency is anticipated to be the most prevalent micronutrient deficiency globally, the most frequent cause of anemia. Our objective was to determine frequency of Iron Deficiency Anemia (IDA) among patients with H. Iron deficiency anemia was seen in 42 patients (37.5%). H. Pylori infection is a frequent cause of iron-deficiency anemia of previously unidentified origin among adults

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Discussion

Conclusion