Abstract
Objective:This prospective study was undertaken to assess the frequency of gestational diabetes mellitus (GDM) and the associated risk factors during pregnancy.Methods:The sample consisted of 650 pregnant women who had no known risk factors for GDM and were followed-up at the Outpatient Clinic for Pregnant Women, Corum State Hospital between March 2009 and June 2010. The data were expressed as percentage, arithmetic mean, standard deviation and chi-square test.Results:Of the 650 pregnant women, 45 were diagnosed with GDM during the study period (6.9%). A statistically significant correlation between GDM and advanced age, family history, and body mass index was found, while no significant correlations existed between GDM and the frequency of pregnancy, number of pregnancy, parity, and number of live births.Conclusion:Advanced age, high body mass index and family history of diabetes mellitus emerged as risk factors for GDM in our study.
Highlights
Gestational diabetes mellitus (GDM) is a glucose tolerance disorder of any severity occurring for the first time or diagnosed during pregnancy.[1,2]
Data Collection Form For Descriptive Characteristics of Diabetic Women: The form included a total of 10 items that address certain socio-demographic, obstetric and diabetes-related characteristics
Data Assessment: During the study period, the first 50 g oral glucose tolerance test (OGTT) was performed between 24 and 28 weeks of the pregnancy, and a second 100 g OGTT was administered to those with a glucose value of ≥ 135 mg/dl, according to the diagnostic criteria proposed by The American Congress of Obstetricians and Gynecologists (ACOG, 2001).[13]
Summary
Gestational diabetes mellitus (GDM) is a glucose tolerance disorder of any severity occurring for the first time or diagnosed during pregnancy.[1,2] The reported global prevalence of GDM ranges between 1% and 14%.3-7. Diabetogenic effect of pregnancy is thought to play a role in the development of GDM where human placental lactogenic hormone (HPL) secreted from placenta during pregnancy results in insulin desensitization leading to physiological. 1. Nuriye Buyukkayaci Duman, Assistant Professor, Hitit University School of Health, Corum, Turkey. Correspondence: May 7, 2014 September 26, 2014 October 3, 2014 increases in blood glucose levels, during the 2nd and 3rd trimesters.[8] increase in the circulating levels of growth hormone, cortisone, estrogen and progesterone is considered to play a contributing role for the insulin resistance.[6,7]
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