FREQUENCY OF CUTANEOUS MANIFESTATIONS IN PATIENTS Of END STAGE RENAL DISEASE ON HAEMO-DIALYSIS

Abstract

Abstract Background: Chronic Kidney Disease (CKD) is a serious disease in which some type of replacement (renal transplant or dialysis) is required. End Stage Renal Disease (ESRD) is the name given to Stage 5 CKD. Various cutaenous manifestations are associated with it which may be due to the disease itself or caused by its treatment. Objectives: This study was conducted to determine the frequency of cutaneous manifestations in patients Iftikhar U. 1 Senior Registrar, Department of Dermatology Unit - II, Mayo Hospital, Lahore Anees M. 2 Head of Nephrology Department KEMU / Mayo Hospital, Lahore Nadeem M. 3 Associate Professor, Department of Dermatology Unit - I KEMU / Mayo Hospital, Lahore Aman S. 4 Head of Dermatology Department SIMS / Services Hospital, Lahore Kazmi A.H. 5 Registrar / Chairman Department of Dermatology KEMU / Mayo Hospital, Lahore of end stage renal disease undergoing haemodialysis. Material and Methods: One hundred patients under-going maintenance haemodialyis in the Department of Nephrology, KEMU / Mayo Hospital, Lahore were examined from January to June, 2011, through spe-cially designed proformas, to determine the presence of cutaneous manifestations in these patients. Results: There were 58 males and 42 females with a mean age of 50 ± 4 years. Overall frequency of cuta-neous manifestations was 82%. The commonest find-ings were xerosis 78% and pruritus 64%. Others were pallor 62%, hyperpigmentation 54%, nail changes 48%, infections 37%, hair changes 35% and mucosal changes 22%. Some rare manifestations seen were arteriovenous shunt dermatitis, acquired perforating disorders, calcification and nephrogenic fibrosing der-matopathy. Conclusion: Cutaneous and mucosal findings are a common problem in patients of ESRD and those undergoing long-term haemodialysis. The commonest are xerosis and pruritus followed by involvement of hair, nails and mucous membranes. Key Words: Chronic kidney disease, End stage renal disease, Haemodialysis, Xerosis.