Frequency and reliability of histologic subtype classification in invasive and in situ melanoma treated with Mohs micrographic surgery

Abstract

To the Editor: National Comprehensive Cancer Network (NCCN) guidelines for melanoma state that Mohs micrographic surgery (MMS) may be considered for melanoma in situ (MIS) of lentigo maligna or acral lentiginous subtype or minimally invasive lentigo maligna melanoma subtype. NCCN guidelines also state that MMS may be considered for minimally invasive melanomas on specialty anatomic sites. It is unclear if indications for MMS are histologic subtype, anatomic site, or both.