Frequency and anti-biogram pattern of enterococci species isolated from various clinical samples in Shahid Mohammadi Hospital, Bandar-Abbas, Iran

Abstract

Background: Antibiotic-resistant pathogens are problem in many geographic areas special in nosocomial infection and ICU admitted patients. Life threatening infections due to multi-drug resistant gram negative microorganism are a medical emergency problem in hospitals. This study aim was evaluation of antimicrobial susceptibility of gram negative bacilli in nosocomial infection. Methods: In a cross sectional study in general hospital Tehran (Iran) during one year (2011), samples of patients with criteria of nosocomial infection by National Nosocomial Infections Surveillance System (NNIS)) were cultured and evaluated by disc diffusion methods, for six antibiotics (Ceftazidim, ciprofloxacin, ceftriaxone, imipenem, Gentamicin, Trimethoprim-sulfamethoxazo)l. Results: In this study 372 positive samples were evaluated. The most common site of isolation was urinary system. The most common isolated organisms were E.coli (2/69%), Pseudomonas aeruginosa (57/19%) Kelebsiella pneumoniae (4/7%). Resistance of E.coli to Imipenem, ceftazidime, ceftrixone, ciprofloxacin, Gentamicin and Trimethoprim-sulfamethoxazol respectively was 86.7%, 94.25%, 95.25%, 88.25%, 77%, 91.75% and pseudomonas aerugenosa resistance respectively was: 93%, 93%, 95.5%, 93.75%, 90%, 95.50% and also Kelebsiella pneumoniae resistance respectively was: 93%, 97.25%, 97.25%, 94.50%, 85.50%, 94.50%. Conclusion: Antimicrobial resistance is an emerging problem. Continuous monitoring of antimicrobial susceptibility and strict adherence to infection prevention guidelines are essential to eliminate major outbreaks in the future.