Abstract

To document the frequency distribution of lonescu-Shiley (IS) bovine pericardial xenograft valve sounds, a study was conducted on three groups of clinically stable subjects with valves implanted for less than 5 years. These groups consisted of 61 subjects with aortic IS valves, 28 subjects with mitral IS valves and 18 subjects with mitral Hancock porcine xenograft valves. Multiple comparisons with a Scheffe with mitral Hancock porcine xenograft valves. Multiple comparisons with a Scheffe test at level a=0.01 showed that the spectral characteristics of closing sounds produced by normal IS and Hancock xenografts implanted in the mitral position were both significantly different from those of IS xenografts implanted in the aortic position but not significantly different from each other. In addition, the spectral distribution of IS closing sounds was highly reproducible and very slightly affected by the duration of the implant up to 5 years.

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