Abstract
Background. This is a community-based, prospective, and analytical study aimed to determine the frequencies of Rhesus blood group (Rh) alleles, haplotypes, and probable genotypes, and establishing baseline data. Materials and Methods. Following informed consent, a total of 1,000 venous blood samples from unrelated individuals were collected. Particle gel immunological diffusion and slide agglutination procedures were used to screen red blood cells for common Rhesus antigens. The frequencies of genes/alleles and haplotypes, as well as the most likely genotypes, were determined. Jaccard's coefficient of similarities was used to calculate similarities between different Sudanese populations. The same coefficient was used to figure out where these people came from. Results. The ē, and the D genes were the commonest alleles detected with frequencies of 98.4%, 93.8% and 90.7% respectively. The C and the E genes were the least frequent with 58.4% and 21.0% frequencies respectively. The Commonest Rh genotype encountered was the (frequency= 44.2%). The and genotypes were detected with lower frequencies of 21.7% and 10.9% respectively, while , and genotypes were the least common [frequencies 0.3%), 0.2% and 0.1% respectively]. The most probably common haplotypes complex was / (frequency= 44.2%) and the least common was / (frequency= 0.1%). Conclusion- The antigen e was found to be the most frequent in major Sudanese populations, when the frequency of E antigen was the least once. the frequency of c antigen among this study populations exhibited high frequency (99).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Medical Laboratory Research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
