Abstract
Thyroid screening is done in our center as recommended by AAP during the first week of life in all preterm as well as term infants in the NICU. During the past 6 months, 8 infants received complete laboratory evaluation due to low T4. The tests performed were T4 by RIA, TSH by RIA and Free T4 by RIA "Amersham Kit" method. Initial values revealed the following:Further evaluation with time, including TRH stimulation test in two of these infants, suggested normal thyroid function. TSH increased from 5, 7 μIU/dl to 50.9, 32.0 μIU/dl at 30 minutes, and 46.4, 23.6 μIU/dl at 60 minutes, respectively after TRH stimulation in the two premature infants. This data suggests that Free T4 does not provide accurate evaluation of thyroid function in premature infants as it does in adults. This paper describes serum Free T4 values in very low birth weight infants.
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