Abstract

The present study was undertaken to investigate the effect of Tribulus alatus extracts on free serum testosterone in male rats. Free serum testosterone level was measured in male rats treated with alcoholic extracts of the aerial part without fruits, fruits of Tribulus alatus and their fractions. All tested extracts showed significant increase in the level of free serum testosterone when compared to that of corresponding control, p < 0.05. Statistical comparison of all groups revealed that the maximum level was found in groups treated with chloroformic and ethanolic fractions of fruits extract. Tribulus alatus extract appears to possess aphrodisiac activity due to its androgen increasing property.

Highlights

  • In traditional medicine a variety of plants have been used as sex stimulants [1]

  • Table-1 represents mean free serum testosterone level among group of rats treated with 70 % alcoholic extracts of Tribulus alatus

  • Table-2 illustrates mean free serum testosterone level among groups of rats treated with different fractions of 70% alcoholic extracts of the aerial part without fruits of T. alatus

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Summary

INTRODUCTION

In traditional medicine a variety of plants have been used as sex stimulants [1]. Arabs have made use of herbal drugs to improve sexual performance and increase libido [2]. In African traditional medicine, especially in Cameroon, Zingiber officinale and Pentadiplan-dra brazzeana are used as aphrodisiac and male sexual stimulation [3]. The genus Tribulus of the Zygophyllaceae comprises ca 20 species that grow as shrubs or herbs in subtropical areas around the world [5].Among the Tribulus species T. terrestris, T. cistoides and T. alatus have been phytochemically investigated and isolation of steroidal saponins from these plants was reported [6,7,8]. The present study was undertaken to investigate the effect of Tribulus alatus extracts on free serum testosterone in male rats

MATERIALS AND METHODS
RESULTS
CONCLUSION
Puri HS
Hegnauer R

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