Abstract
Background 3D cardiac MRI has long held promise for improved heart coverage, higher resolution, and reduced sensitivity to poor breath-hold reproducibility. However, its use has been limited by reduced blood pool to myocardium contrast for spoiled and balanced steady-state free precession (bSSFP) implementations. T2-preparation techniques [1] are capable of increasing contrast but are unfortunately limited by lengthy preparation periods and resulting scan inefficiencies. In this work, we develop a paradigm for high contrast 3D cardiac function that relies on the alternative use of magnetization transfer (MT) preparation [2] combined with accelerated 3D spoiled gradient echo imaging (SPGR).
Highlights
3D cardiac MRI has long held promise for improved heart coverage, higher resolution, and reduced sensitivity to poor breath-hold reproducibility
An off-resonance RF pulse was interleaved with wholeheart, respiratory gated 3D radial spoiled gradient echo imaging (SPGR) sampling [3]
In-vivo experiments utilized a 1600°, 20 ms Hamming-windowed Sinc pulse applied every 10 TRs. This pulse was applied at 210 Hz off-resonance providing some fat-saturation
Summary
Free-breathing 3D cardiac function with accelerated magnetization transfer prepared imaging. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. Background 3D cardiac MRI has long held promise for improved heart coverage, higher resolution, and reduced sensitivity to poor breath-hold reproducibility. Its use has been limited by reduced blood pool to myocardium contrast for spoiled and balanced steady-state free precession (bSSFP) implementations. T2-preparation techniques [1] are capable of increasing contrast but are limited by lengthy preparation periods and resulting scan inefficiencies. We develop a paradigm for high contrast 3D cardiac function that relies on the alternative use of magnetization transfer (MT) preparation [2] combined with accelerated 3D spoiled gradient echo imaging (SPGR)
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