Abstract

This content was analysed in patients with chronic periodontitis and in control subjects. In periodontal disease, it was characterized by higher mean concentrations of glycine, proline, tyrosine and (δ-aminovaleric acid than in controls ( p < 0.001). However, the range of values varied considerably in the two groups. There were differences between periodontitis and control samples in the proportions of proline to serine ( p < 0.01) and proline to glutamic acid and glutamine ( p < 0.05). Bacterial contamination and decomposition of salivary proteins is responsible for the elevated salivary levels of glycine, proline, tyrosine and δ-aminovaleric acid in the periodontal group.

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