Abstract

F PARKES WEBER (Figs 1 and 2) died June 2 in his 100th year. 1 He distinguished himself in medicine as a keen observer and as an eagerly curious and tireless student of disease, particularly the unusual. Few others, if any, have given their name to so many diseases. The three best known of the Weber eponyms are: (1) Osler-Rendu-Weber's hereditary hemorrhagic telangiectasia 2 ; (2) Sturge-Weber disease 3 —hemangiectatic nevus of the face and cerebral meninges; and (3) Weber-Christian disease 4 —relapsing febrile nodular nonsuppurative panniculitis. But others are the Weber-Klippel syndrome 5-7 — hemangiectatic hypertrophy of the limbs (see Fig 3 for an example); Vaquez-Osler-Weber disease 8,9 —polycythemia vera with splenomegaly; Weber-Cockayne familial recurrent bullous eruption of the hands and feet, 10 which is a form of localized epidermolysis bullosa. 11,12 Weber's voluminous writings, numbering over 1,200, began in 1890 with a paper on abnormal foramina in the

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