Frecuencia de alteraciones en el perfil de litiasis de pacientes con obesidad

Abstract

BackgroundUrolithiasis is one of the main urologic problems present in obese patients. Even though there are multiple mechanisms by which this relation can be explained, there is currently little information on the relation between both morbid obesity (BMI>35kg/m2) and super obesity (BMI>50kg/m2) and the risk for developing renal lithiasis and its possible consequences. AimsTo evaluate the alterations in the lithiasis profile of patients with obesity, morbid obesity, and super obesity. MethodsA cross-sectional study was designed in which patients in the obesity consultation follow-up of the Medical Attention for Patients with Obesity Program (PAPO for its Spanish initials) of the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ) were invited to participate in the evaluation of lithiasis profile alteration frequency. Demographic and clinical variables were obtained and a pre-stone burden and post-stone burden lithiasis profile was requested. The patients were classified into 3 groups in accordance with their BMI and the altered variables of the lithiasis profile were analyzed. ResultsNinety-six patients enrolled in the PAPO were invited to participate in the study and 24 of them accepted. The mean age was 40.1±10.5years, mean weight was 124.9±31.9kg, mean height was 163.9±10.3cm, and mean BMI was 46.9±11.2kg/m2. Our analysis revealed that 83% of the patients had at least one alteration in their lithiasis profile, and the morbid obesity group had the greatest number of lithiasis profile abnormalities. ConclusionsA high frequency of alterations in the lithiasis profile was identified in patients presenting with obesity.