Abstract
Unexplained hematuria may be presenting feature of various systemic illnesses such as coagulation disorder, anticoagulation therapy, leukemia, disseminated intravascular coagulation and multiorgan dysfunction. Bleeding is a common presenting feature of acute leukemia. This may occur in any mucosal surface of body. A 52-year-old male presented with complaints of low grade fever, and gross hematuria for last three days. He was diagnosed as a case of acute myeloid leukemia on the basis of bone marrow aspiration and cytochemistry. Presentation of acute leukemia with gross hematuria is uncommon. Gross hematuria as the sole presenting feature in such cases is unusual and only few cases have been described in literature.
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