Abstract
The occurrence of Francisella tularensis outside of endemic areas, such as North America and Eurasia, has been enigmatic. We report the metagenomic discovery and isolation of F. tularensis ssp. holarctica biovar japonica from diseased ringtail possums in Sydney, Australia. This finding confirms the presence of F. tularensis in the Southern Hemisphere.
Highlights
The occurrence of Francisella tularensis outside of endemic areas, such as North America and Eurasia, has been enigmatic
Tularemia is endemic to parts of the Northern Hemisphere, including North America and Eurasia, and most cases in humans are caused by the F. tularensis subspecies tularensis and holarctica
The Study As part of a wider study of neglected and undiagnosed disease syndromes observed in Australia wildlife, we investigated the possible infectious cause of several deaths in ringtail possums that were most often associated with acute necrotizing enteritis or hepatitis
Summary
The occurrence of Francisella tularensis outside of endemic areas, such as North America and Eurasia, has been enigmatic. Tularemia is a highly infectious zoonotic disease caused by the bacterium Francisella tularensis that affects humans and other animals [1,2]. Sintchenko, E.C. Holmes); Westmead Institute for Medical Research, Westmead, New South Wales, Australia
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