Abstract

analyses the independent prognostic factors according to the histology of the primary tumor are as follows: Breast e KPS < 70% (HR Z 1.84); no PTC (HR Z 1.47), no chemotherapy [CT] (HR Z 1.49); no RS (HR Z 2.34). Lung e KPS < 70% (HR Z 1.80); no PTC (HR Z 2.10); no FT (HR Z 2.90 for RS and 1.72 for SG, respectively). Melanoma e no FT (HR Z 4.38 for RS and 2.28 for SG, respectively). GI e no SG (HR Z 4.19). All tumors e KPS < 70% (HR Z 1.70); no PTC (HR Z 1.42); no CT (HR Z 1.42), no FT (HR Z 2.48 for RS and 2.11 for SG, respectively); ECM (HR Z 1.48). *All p value < 0.05. Conclusions: Comparing our data to DS-GPA we observe differences in prognostic factors for breast cancer (PTC, CT and FT), lung cancer (PTC and FT), melanoma (FT) and GI (FT). ECM was just significant when it was analyzed all tumor types together and the number of BM was not an independent factor in this study. The FT was correlated with improved survival in all tumor histology. The inclusion of new prognostic factors could further refine DS-GPA. Author Disclosure: M.G. Silva: None. D.F.G. Neves: None. F.L.C. Faustino: None. D.F. Ferreira: None. A.C.A. Pellizon: None. R.C. Fogaroli: None. D.G. Castro: None. M.J. Chen: None.

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