Frailty level at discharge predicts mortality in older patients with Clostridioides difficile more accurately than age or disease severity

Abstract

Key summary pointsAimTo calculate mortality rates in older patients with Clostridioides difficile infection (CDI) and compare multidimensional frailty level, CDI severity and age as predictors of mortality.FindingsOlder patients with their first CDI had a high 90-day mortality of 28%. Multidimensional frailty assessment at discharge outperformed CDI severity and age in predicting 90-day mortality among older patients with CDI.MessageCompared with age and CDI severity, the multidimensional frailty assessment is the best predictor of 90-day mortality in older patients with CDI.