Abstract
In recent years, there has been increasing interest in the frailty as a prognostic factor of acute myocardial infarction in elderly patients. Frailty is an important prognostic marker of frequent complications, readmission to hospital, high hospital mortality and major cardiovascular events in elderly patients with acute myocardial infarction. This category of persons is often not allowed to undergo invasive interventions and are often excluded from the recommended treatment, and they tolerate cardiac surgery worse, recovery from illness is slower, functionality decreases, then disability and death develop. The present review aims to investigate the impact of frailty on management of elderly patients with acute myocardial infarction (AMI). To analyze the literature, we searched for information on this issue in PubMed / MEDLINE, PMC, Web of Science, Scopus, The Сocrane Library. The search depth was 15 years: from 2006 to 2021. One of the important factors in improving clinical outcomes, improving the quality of life in elderly patients with acute myocardial infarction is the early detection of frailty. Frailty assessment is a valuable tool for risk stratification that can be helpful to clinicians in deciding the optimal pathway for management and treatment strategies. Risk prediction is also important for deciding secondary prevention and cardiac rehabilitation measures in the elderly with acute myocardial infarction.
Highlights
Life expectancy of population is increasing globally
The present review aims to investigate the impact of frailty on management of elderly patients with acute myocardial infarction (AMI)
The results showed that general prevalence of pre-frailty in low-income countries was 49,3%, ranging from 13,4% in Tanzania and 40,7%-71,6% in Brazil
Summary
Life expectancy of population is increasing globally. According to the report by the United Nations, the share of the population aged 60 years or over is expected to rise from 617 million persons in 2015 to 2,1 billion by 2050 with the highest proportion of elderly persons in Asia [1].Older individuals comprise a diverse cohort of population. European multicenter observational cohort study with 1564 enrolled patients by Jonathan Hewitt et al has identified that among patients with COVID-19 with mean age of 74 years, frailty prevalence was 49,4% (5-8 according to CFS scale) and mortality was 27,2%. The analysis of study indicated a high mortality risk and prolonged hospitalization in frail elderly patients with COVID-19 (p
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