Abstract
Acinetobacter baumannii can cause many diseases including septiceamia, pneumonia, meningitis, soft tissue and urinary tract infections. Herein, we described the synthesis of one trisaccharide and two tetrasaccharide fragments derived from A. baumannii ATCC 17961 O-antigen, which can be used for screening novel glyco-epitope and developing synthetic carbohydrate-based vaccine against A. baumannii infection. The overall yields for the synthesis of trisaccharide 1, tetrasaccharide 2 and tetrasaccharide 3 are 26.8% (8 steps), 21.6% (9 steps) and 24.5% (6 steps), respectively.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.