Fragility and its relationship with geriatric syndromes in a mexican population of elderly adults in a third‐level hospital

Abstract

AbstractBackgroundFrailty refers a term which describes general state of health that is characterized by an increased susceptibility or vulnerability for stressors as a consequence a deterioration of physiological reserves. Frailty have been associated to multiple Geriatric syndromes, higher rates on mortality and increased risks for poor outcomes, including Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI), which are conditions that may be common in older adults.MethodThis report is a secondary analysis from a transversal study, the inclusion criteria include adults from 60 or older, who complete evaluations at the baseline in a from a dementia clinic at a tertiary care center in Mexico. We exclude pre‐fragile and robust participants at the baseline, the analytical simple comprised 700 older adults. Frailty was established using the FRAIL criteria the presence of 3 or more remaining criteria was considered frailty. Sociodemographic variables, comorbidities, and geriatric syndromes were considered for the analysis.ResultA total of 700 older adults were evaluated and 242 (34.5%) were diagnose with Frailty. Comorbidities such as diabetes (41.7%), high blood pressure (64%) and osteoarthritis (50%) were prevalent with frailty. Female sex (63.6%) and marital status marriage (55%) were prevalent with frailty. The incidence of mild dementia was 35.1% and 28.9% for mild cognitive impairment. Multiple logistic regression was performed finding an OR (95% CI) P <.001 in the association of frail patients in the 60‐70 age group, the association of the female sex with frailty present in OR (95% CI). P .023 and being married OR (95% CI) P < .001.ConclusionIn Mexican older adults from the clinical population, the results demonstrated that frailty was associated with mild cognitive impairment and mild dementia as well as female sex, married marital status, and age. It would be necessary to compare with other groups without frailty to demonstrate the consistency of these findings as potential risk factors.