Fractionation of hydrolysate from corn germ protein by ultrafiltration: In vitro antidiabetic and antioxidant activity

Amin Karimi,Mohammad Hossein Azizi,Hassan Ahmadi Gavlighi

doi:10.1002/fsn3.1893

Abstract

In Karimi, Azizi, and Ahmadi Gavlighi (2020), the word “Frationation” in the article title was incorrect, it should be “Fractionation” so it reads “Fractionation of hydrolysate from corn germ protein by ultrafiltration: In vitro antidiabetic and antioxidant activity.” This has also been corrected in the online version. REFERENCE Karimi, A., Azizi, M. H., & Ahmadi Gavlighi, H. (2020). Fractionation of hydrolysate from corn germ protein by ultrafiltration: In vitro antidiabetic and antioxidant activity. Food Science Nutrition, 8(5), 2395–2405. 10.1002/fsn3.1529

Highlights

In view of food industry and human health, prevention of lipid oxidation and generation of free radicals in the foodstuff and living body tissue are important for control of quality of food and diseases (Zhang et al, 2016, 2019)
| 2396 disaccharides to glucose, and as results, less glucose is absorbed in the small intestine (Vilcacundo et al, 2017). Another approaches for control of diabetes are through inhibition of dipeptidyl peptidase-IV (DPP-IV) activity that increases the half-life of total circulating GLP-1 by preventing it from degradation and inactivation
The highest degree of hydrolysis (DH) value of hydrolysates was 17.5 ± 0.2%, which was obtained by alcalase, while that of the Corn germ protein hydrolysate (CGPH) produced by flavourzyme was

Summary

| INTRODUCTION

In view of food industry and human health, prevention of lipid oxidation and generation of free radicals in the foodstuff and living body tissue are important for control of quality of food and diseases (Zhang et al, 2016, 2019). | 2396 disaccharides to glucose, and as results, less glucose is absorbed in the small intestine (Vilcacundo et al, 2017) Another approaches for control of diabetes are through inhibition of dipeptidyl peptidase-IV (DPP-IV) activity that increases the half-life of total circulating GLP-1 (peptides that stimulates glucose-dependent insulin secretion in pancreatic β-cells) by preventing it from degradation and inactivation. In the past few years, enzyme inhibitors have developed for control of the type 2 diabetes In this concept similar to α-amylase and α-glucosidase inhibitor, concern about synthetic drugs and toxicity and side effect should be noticed and using of natural and safe inhibitors as antidiabetic agents is considered (Wang et al, 2019). In this study, the ability of three proteases (alcalase, flavourzyme, trypsin) to generation hydrolysate from corn germ protein was evaluated and antioxidant activity and DPP-IV, α-amylase and α-glucosidase inhibitory activity of hydrolysates, and their fractions were investigated. The htot of this equation was 7.75 meq/g (Zhang, Pang, & Xu, 2011)

| MATERIALS AND METHODS

| RESULTS AND DISCUSSION

| CONCLUSIONS