Abstract
anticonvulsants more frequently had higher estimations of the maximum two-week risk of seizures (Kruskal-Wallis p < 0.001). For example, respondents who used anticonvulsants ‘always’ or ‘usually’ had a median estimate of the maximum seizure risk of 10%, while those who responded ‘never’ estimated the risk to be 3%. Conclusion: There is wide variability in the use of prophylactic steroids and anticonvulsant medications for patients undergoing SRS. Further investigation of the actual seizure risk after SRS and the risks and benefits of prophylactic medications is warranted, and may lead to more patientcentered, rational prescribing practices, to minimize toxicity and cost and maximize clinical utility. Author Disclosure: N.D. Arvold: None. N.E. Pinnell: None. A. Mahadevan: None. S. Connelly: None. R. Silverman: None. S.E. Weiss: None. P.J. Kelly: None. B.M. Alexander: None.
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