Abstract
Background and Aims: Creating an environment of maximal hyperemia is required for adequate fractional flow reserve (FFR) measurements and ultimately an effective percutaneous intervention. Currently the gold standard method is via intravenous adenosine, but it has side effects through it non-selective activation of adenosine receptors. Intravenous regadenoson has been proposed as a safe alternative, but a recent trial used regadenoson with aminophylline. The goal of this meta-analysis is to compare the previous four studies with this newly designed trial.
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