FP07.09 Detection of Early Lung Cancer from Average-Risk Individuals and from Benign Nodule Carriers with a DNA Methylation Blood Test

Abstract

Early detection is the key to reducing the death of lung cancer. An effective blood-based method for the early diagnosis of lung cancer has not yet been developed. Meanwhile, current strategies to differentiate benign and malignant lung nodules are also in lack of accuracy. Here we describe a blood test that can detect lung cancer early from average-risk individuals and from benign lung nodule carriers through assessment of a methylation panel of 8 genes in peripheral blood DNA.