Abstract
Immortality has always been an issue of curiosity among scientific community. Hydra's indefinite self renewal capacity of stem cells has attracted natural scientists to seek insights about longevity studies in humans. Three stem cell lineages ectodermal and endodermal epitheliomuscular stem cells and interstitial stem cells contribute to indefinite self renewal capacity of epithelial cells. Moreover, forkhead boxO (foxO) which plays a key role in increased life span in lower creatures like flies and worms has shown to have a strong association of FoxO3a gene in human longevity and maintainence of adult haematopoitic stem cells and neural stem cells. doi : 10.5214/ans.0972.7531.200107
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