Abstract
Fourier transform infrared spectroscopic imaging (FTIRI) system can simultaneously collect molecular spectra and morphological information by effectively integrating Fourier transform infrared spectroscopy (FTIRS) and microimaging technique. Thus, the components and molecular structure at micro-specimen can be obtained by FTIRI analysis. This paper introduced the development, operating principle and features of FTIRI, especially the research on cartilage by FTIRI that has become a new research area in biomedical optics. The typical findings and progress of the researches on normal and osteoarthritic cartilages (degeneration) by FTIRI were reviewed in detail, as well as the limitations and prospects of FTIRI in future.
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