Abstract
Background and objective: Botulinum toxin type A (BoNT-A) has been reported to be an effective treatment for limb spasticity after stroke. However, few studies have reported improvements in the active motor function in poststroke patients with spastic upper limb hemiparesis. The aim of this study was to assess the clinical influence of four periodical BoNT-A injections, followed by special instructions for a home-based functional training on not only passive but also active motor functions in poststroke patients with severe upper limb hemiparesis with spasticity.
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