Abstract
Two novel cyclic hexapeptides, comoramides A and B and two new cyclic heptapeptides, mayotamides A and B were isolated, separately, from two collections of the compound ascidian Didemnum molle collected at two spots of the lagoon of Mayotte. The structure of all four peptides, including the absolute configuration of all amino acids, was elucidated by spectroscopic analysis, mainly NMR data, and degradation experiments. All four compounds exhibit mild cytotoxicity against several tumor cells. Obtaining four new cyclic peptides from two D. molle collections, which add to the two earlier reported cyclic peptides from an Australian and Philippine D. molle, supports the notion that these compounds originate from prokaryotic algal symbionts.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
