As a new independent subject, biophysics emerged in the early 1950's. The Institute of Biophysics, Chinese Academy of Sciences, was established in 1958. It was the milestone of the beginning of biophysics in China. This review introduces the foundation and the early development of biophysics in China, and the establishment of the interdisciplinary subjects, including radiation biology, bio-cybernetics, astrobiology, and bionics.

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