Abstract
The key problem that limits the practical applications of nonenzymatic electrochemical sensors in biological media, is the biofouling and chemical fouling of electrodes due to the adsorption of biological molecules and oxidation (reduction) products. Electrode fouling will cause low accuracy, poor stability, and low sensitivity. Here, a simple and efficient antifouling electrode was demonstrated for electrochemical sensing based on covalent-organic framework (COF) TpPA-1 and carboxylic multi-walled carbon nanotubes (CNT) composites. COF TpPA-1 possesses abundant hydrophilic groups, which assisted the dispersion of CNT in water and formed uniform composites by π-π interaction. In addition, the introduction of CNT into the composites improved the electron transfer rate of COF TpPA-1. The antifouling interface was characterized by electrochemistry, contact angle measurement, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS). The electrode showed good chemical and bio-fouling resistant performance for the electrochemical detection of β-nicotinamide adenine dinucleotide (NADH) and uric acid (UA) in real serum samples.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
